Increased levels of lipid peroxides as predictive of symptomatic vasospasm and poor outcome after aneurysmal subarachnoid hemorrhage
Author(s) -
Takao Kamezaki,
Kiyoyuki Yanaka,
Sohji Nagase,
Keishi Fujita,
Noriyuki Kato,
Tadao Nose
Publication year - 2002
Publication title -
journal of neurosurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.564
H-Index - 210
eISSN - 1933-0693
pISSN - 0022-3085
DOI - 10.3171/jns.2002.97.6.1302
Subject(s) - subarachnoid hemorrhage , medicine , vasospasm , cerebral vasospasm , cerebrospinal fluid , complication , lipid peroxidation , anesthesia , gastroenterology , cardiology , oxidative stress
Cerebral vasospasm remains a devastating medical complication of aneurysmal subarachnoid hemorrhage (SAH). Reactive oxygen species and subsequent lipid peroxidation are reported to participate in the causes of cerebral vasospasm. This clinical study was performed to investigate the relationships between levels of lipid peroxides in cerebrospinal fluid (CSF) and both delayed cerebral vasospasm and clinical outcome after SAH.
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