Multiple resections for patients with glioblastoma: prolonging survival
Author(s) -
Kaisorn L. Chaichana,
Patricia L. Zadnik,
Jon Weingart,
Alessandro Olivi,
Gary L. Gallia,
Jaishri O. Blakeley,
Michael Lim,
Henry Brem,
Alfredo QuiñonesHinojosa
Publication year - 2012
Publication title -
journal of neurosurgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.564
H-Index - 210
eISSN - 1933-0693
pISSN - 0022-3085
DOI - 10.3171/2012.9.jns1277
Subject(s) - medicine , glioblastoma , surgery , multivariate analysis , survival analysis , proportional hazards model , adjuvant therapy , log rank test , chemotherapy , cancer research
Glioblastoma is the most common and aggressive type of primary brain tumor in adults. These tumors recur regardless of intervention. This propensity to recur despite aggressive therapies has made many perceive that repeated resections have little utility. The goal of this study was to evaluate if patients who underwent repeat resections experienced improved survival as compared with patients with fewer numbers of resections, and whether the number of resections was an independent predictor of prolonged survival.
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