Open AccessConventional and Novel Treatment Strategies to Combat COVID-19 along with Review of most Affected Countries
Author(s) -
Umair-Ul-Hassan,
Rana Muhammad Awais Khan,
ShafiqurRehman,
Amjad Khan
Publication year - 2020
Publication title -
global drug design and development review
Language(s) - English
Resource type - Journals
eISSN - 2788-497X
pISSN - 2788-4120
DOI - 10.31703/gdddr.2020(v-i).03
Subject(s) - pandemic , covid-19 , genome , virus , china , virology , crispr , medicine , intensive care medicine , biology , political science , disease , outbreak , genetics , infectious disease (medical specialty) , law , pathology , gene
This review illustrates a comparison of currently implemented strategies and the need of a novel technique to cure the COVID-19. Current strategies served a lot to cope up with the situation by decreasing the rate of fatalities i.e. some FDA approved drugs and giving immunity by the plasma proteins of cured patients, however these approaches could not eliminate the pandemic from the society emphasizing that some advance technology need to be considered in order to fight with SARS-COV-2 virus. CRISPR-Cas based approach to inactivate the virus before its fusion with host DNA has been successful in in-vitro studies performed at Stanford University along with SHERLOCK & MAMMOTH biosciences who were able to degrade 80 % viral genome. Here we have also done a literature review of major affected countries China, Italy, United states, and India.