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The article presents a “Baseline Study of Scientific Technological Supply of Universities in Chilean Southern Central Macro Region in relation to the Current Status and Projections of Regional Productive Economic Systems”, developed by Universidad del Bio-Bio for the Higher Council of Education (CSE). It points that the connection between scientific technology supply and demand in Chile represents a challenge for regional innovation systems. So, it aims to generate basic knowledge about scientifictechnological supply and demand in Chilean southern central macro region. It suggests that it is at regional level where there is a higher density of connections which capitalize complex knowledge, a key factor for development.

Oferta científico-tecnológica de la macro región centro sur de Chile y su relación con sistemas productivos regionales