DOES THE REALISTIC CONTACT AND DAILY USE CONDITIONS LIMIT THE USE OF POLYCARBONATE BABY BOTTLES FOR MIGRATION AND RESIDUE LEVEL OF BISPHENOL-A

Bisphenol-A (BPA) which is a plastic monomer acting as endocrine disruptor, can cause developmental effects and change the metabolism even at low concentrations. This study was carried out to make (i) a general assessment by performing residue analysis on the polycarbonate baby bottles, (ii) determining the factors affecting the migration of BPA to the food and (iii) determining the effect of repetitive procedures on PC baby bottles in daily use. Amount of residual BPA ranged from 0.60 ±0.05 ppm to 6.23 ±0.24 ppm and BPA migration could not be detected in any of contact conditions. Estimated daily intakes of BPA via infant formula in PC baby bottle were calculated as  1.8 µg kg -1 bw day -1 for a 3 month-old infant  and 1.22 µg kg -1 bw day -1 for a 6 month-old  infant which was lower than but very close to the latest value of t-TDI (4 µg kg -1 bw day -1 ) determined by EFSA. Sterilization procedures changed the amount of residual BPA significantly. Although it is concluded that the use of brand-new PC baby bottles does not pose a risk to health, sterilization procedures can lead to the higher amounts of migrated BPA which can be toxically important.