A RESETTABLE HIGH-DENSITY MICROFLUIDIC PARTICLE TRAPPING SYSTEM | Zendy

Ryan D. Sochol | Zendy; B. Lüthi | Zendy; Kosuke Iwai | Zendy; Megan E. Dueck | Zendy; Lydia Lee | Zendy; Liwei Lin | Zendy

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A RESETTABLE HIGH-DENSITY MICROFLUIDIC PARTICLE TRAPPING SYSTEM

Author(s) -

Ryan D. Sochol,

B. Lüthi,

Kosuke Iwai,

Megan E. Dueck,

Lydia Lee,

Liwei Lin

Publication year - 2010

Publication title -

1998 solid-state, actuators, and microsystems workshop technical digest

Language(s) - English

Resource type - Conference proceedings

DOI - 10.31438/trf.hh2010.5

Subject(s) - microfluidics , microscale chemistry , fluidics , microparticle , nanotechnology , bead , materials science , trapping , microbead (research) , chemistry , engineering , electrical engineering , biochemistry , mathematics education , mathematics , chemical engineering , composite material , ecology , biology

Microfluidic bead-based microarrays offer an ideal platform for chemical and biological applications, such as bio-molecule detection, diagnostics and drug screening. Despite the numerous advantages inherent to dynamic bead-based microfluidic arrays, current microparticle trapping methods remain limited in terms of trapping density and device resettability. Here we present a simple, resettable microparticle arraying system by utilizing geometric designs in microfluidics to manipulate microscale hydrodynamics. Under forward fluidic flow, arrays of individual 15 μm diameter microbeads immobilize in designated trapping positions between microposts. Under backward fluidic flow, the arrayed microbeads release rapidly to reset the microfluidic device.

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