Successful treatment ofBacillus cereusgroup brain abscesses with a combination of high-dose ciprofloxacin and vancomycin

Central nervous system (CNS) infections (e.g., brain abscess, meningitis) caused by members of the Bacillus cereus group are rare, but the associated crude mortality is significant. The optimal antimicrobial regimen for patients with these infections remains poorly defined. This report describes a case of multiple brain abscesses in an immunocompromised patient caused by a member of the B. cereus group. The patient was successfully treated with a combination of high-dose ciprofloxacin and vancomycin, providing evidence for the clinical utility of this therapeutic regimen.