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Sertoli-Leydig cell tumours are rare sex stromal tumours with an incidence of &lt; 0.5% of all ovarian tumours. Most frequently this tumour occurs in young women with a history of amenorrhoea, hirsutism and lowered pitch. Here, we report on a woman with IRS, postmenopausal virilization and increased testosterone levels due to a Sertoli-Leydig cell tumour. This is the first case to suggest an association between IRS and Sertoli-Leydig cell tumours. Furthermore, we highlight the difficulties in detecting this ovarian tumour with sonography.

Sertoli-Leydig Cell Tumour in a Postmenopausal Woman Showing all Facets of the Insulin Resistance Syndrome (IRS)