Sertoli-Leydig Cell Tumour in a Postmenopausal Woman Showing all Facets of the Insulin Resistance Syndrome (IRS) | Zendy

Eva Dahlgren | Zendy; Berit Gull | Zendy; Roger Wïllén | Zendy; F. Sundler | Zendy; Thord Rosén | Zendy; PerAnders Jansson | Zendy

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Sertoli-Leydig Cell Tumour in a Postmenopausal Woman Showing all Facets of the Insulin Resistance Syndrome (IRS)

Author(s) -

Eva Dahlgren,

Berit Gull,

Roger Wïllén,

F. Sundler,

Thord Rosén,

PerAnders Jansson

Publication year - 2005

Publication title -

upsala journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.808

H-Index - 41

eISSN - 2000-1967

pISSN - 0300-9734

DOI - 10.3109/2000-1967-068

Subject(s) - virilization , medicine , leydig cell , hirsutism , sertoli cell , testosterone (patch) , endocrinology , stromal cell , insulin resistance , androgen , hormone , insulin , luteinizing hormone , spermatogenesis , polycystic ovary

Sertoli-Leydig cell tumours are rare sex stromal tumours with an incidence of < 0.5% of all ovarian tumours. Most frequently this tumour occurs in young women with a history of amenorrhoea, hirsutism and lowered pitch. Here, we report on a woman with IRS, postmenopausal virilization and increased testosterone levels due to a Sertoli-Leydig cell tumour. This is the first case to suggest an association between IRS and Sertoli-Leydig cell tumours. Furthermore, we highlight the difficulties in detecting this ovarian tumour with sonography.

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