Weekly liposomal amphotericin B as secondary prophylaxis for invasive fungal infections in patients with hematological malignancies | Zendy

Lizbeth CahuaymeZuniga | Zendy; Russell E. Lewis | Zendy; Victor E. Mulanovich | Zendy; Dimitrios P. Kontoyiannis | Zendy

Open Access

Weekly liposomal amphotericin B as secondary prophylaxis for invasive fungal infections in patients with hematological malignancies

Author(s) -

Lizbeth CahuaymeZuniga,

Russell E. Lewis,

Victor E. Mulanovich,

Dimitrios P. Kontoyiannis

Publication year - 2012

Publication title -

medical mycology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.004

H-Index - 86

eISSN - 1460-2709

pISSN - 1369-3786

DOI - 10.3109/13693786.2011.631152

Subject(s) - amphotericin b , medicine , secondary prophylaxis , retrospective cohort study , antifungal , intensive care medicine , surgery , dermatology

There have been no published studies evaluating the efficacy and safety of weekly liposomal amphotericin B as secondary prophylaxis in leukemic patients with invasive fungal infections (IFIs). We found in a retrospective review of our experience with 14 such patients admitted from 2003-2009 that the use of this approach was associated with frequent relapse of IFIs (36%) and kidney injury (36%).

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