Open AccessFactor X deficiency: An uncommon presentation of AL amyloidosis
Author(s) -
Ajaydas T. Manikkan
Publication year - 2012
Publication title -
upsala journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.808
H-Index - 41
eISSN - 2000-1967
pISSN - 0300-9734
DOI - 10.3109/03009734.2012.690457
Subject(s) - medicine , amyloidosis , coagulation , rheumatoid factor , factor x , al amyloidosis , presentation (obstetrics) , amyloid (mycology) , pathology , immunology , surgery , platelet , immunoglobulin light chain , rheumatoid arthritis , thrombin , antibody
Factor X deficiency is the most common coagulation factor deficiency amongst patients with AL amyloidosis. It presumably occurs due to adsorption of factor X to amyloid fibrils. The deficiency of this factor, in conjunction with other hemostatic defects, can cause bleeding complications. A case of acquired factor X deficiency due to AL amyloidosis is reported, where abnormal coagulation parameters were the only presenting feature.
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