One Pot Multicomponent Synthesis of Pyranopyrazoles using Tetra Butyl Ammonium Bromide as Catalyst in Aqueous Media | Zendy

Amol M. Pachpinde | Zendy; Mallinath Langade | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

One Pot Multicomponent Synthesis of Pyranopyrazoles using Tetra Butyl Ammonium Bromide as Catalyst in Aqueous Media

Author(s) -

Amol M. Pachpinde,

Mallinath Langade

Publication year - 2018

Publication title -

international journal for research in applied sciences and biotechnology

Language(s) - English

Resource type - Journals

ISSN - 2349-8889

DOI - 10.31033/ijrasb.5.5.5

Subject(s) - tetra , ammonium bromide , catalysis , aqueous medium , bromide , aqueous solution , ammonium , chemistry , nuclear chemistry , organic chemistry , medicinal chemistry , biochemistry , pulmonary surfactant

A four-component one-pot method to synthesize pyranopyrazoles from aromatic aldehydes, malononitrile, ethylacetoacetate and hydrazinehydrate using tetrabutyl ammonium bromide as a catalyst (20 mol %) in aqueous media is described herein. This method is simple and provides several advantages such as, good yields, short reaction time, environmentally friendly and mild reaction conditions. Use of environmentally benign water as a solvent is also a major advantage of using this method. Keywords-Aromatic Aldehydes; Malononitrile; Ethylacetoacetate; Pyranopyrazoles; TBAB.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research