Evaluaton of hypoglycaemic and wound healing activities of Tiliacora acuminata | Zendy

Ram Mohan Manda | Zendy; Vishwanath Valusa | Zendy; Srinivas Reddy Karka | Zendy; Vamshi Krishna Parshaboina | Zendy; S. Ganapaty | Zendy

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Evaluaton of hypoglycaemic and wound healing activities of Tiliacora acuminata

Author(s) -

Ram Mohan Manda,

Vishwanath Valusa,

Srinivas Reddy Karka,

Vamshi Krishna Parshaboina,

S. Ganapaty

Publication year - 2014

Publication title -

indian journal of pharmaceutical and biological research

Language(s) - English

Resource type - Journals

ISSN - 2320-9267

DOI - 10.30750/ijpbr.2.4.19

Subject(s) - wound healing , alloxan , medicine , aqueous extract , traditional medicine , pharmacology , diabetes mellitus , surgery , endocrinology

Natural products particularly plant origin have pla yed a vital role in prevention and mitigation of human diseases. The present study was carried to evaluate the antihyperglycaemic and wound healing activity of th e leaf Extracts of Tiliacora acuminate (Lam) on rats, the aqueous leaf extract was found to prod uce significant reduction of blood glucose concentration between 2- 4 h of administration in alloxan induced hyperglycaemic rats at tested dose levels. However, in normoglycaemic animals, the extract at 400mg/kg produced significa nt reduction of blood glucose between 2-4 h of administration. In the wound heali ng studies, the leaf juice was found to be more active than the extract.

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