Maternal and Neonatal Complications of Asthma, a Study in Iran

Results: The baseline characteristics of the women in both groups did not show significant differences. Gestational hypertension was more in the asthmatic group [43 (7.37%) VS 26 (3.45%), P=0.001]. Also, the rate of preterm delivery was higher in asthmatic women (72 (12.34%) VS 77 (10.22%) in the control group, P=0.04). However, the rate of preeclampsia was less in the asthmatic group [29 (4.97%) VS 71 (9.42%), P=0.008]. Apgar score at minutes 1 and 5 was less in asthmatic group. Intra Uterine Fetal Demise (IUFD) (24 (4.1%) VS 13(1.7%), P value=0.009), and neonatal death (31 (5.31%) VS 10 (1.32%), P=0.001) were more in the asthmatic group. The maternal and neonatal complications did not show significant differences in various severities of asthma. Multivariate regression model showed more risks for neonatal death (adjusted odds ratio (AOR)=4.18; CI95% 2.03-8.60), IUFD (AOR=2.43; CI95% 1.22-4.82), gestational hypertension (AOR= 1.43; CI 95% 1.40-1.45), and lower risk for preeclampsia (AOR 0.37; CI95%0.17-0.79) in asthmatic women.