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Anticoagulant therapy has been used for the prevention and treatment of deep vein thrombosis and pulmonary embolism (1) after major surgery (2, 3) . Heparin-induced skin necrosis is a rare complication (4), which was first observed in 1973 (5) and their frequency is estimated to be less than 0.2% (6) . It usually happens about 8-11 days after heparin therapy. It could also occur sooner if the patient has any history of the previous reaction to Heparin administration (4) .

A Rare Case of Mortality Following Heparin-induced Necrotizing Skin Lesions as Thromboprophylaxis After Total Abdominal Hysterectomy