Diabetes Increases the Incidence of Levodopa-Induced Dyskinesia in Parkinson’s Disease; A Case-Control Study
Author(s) -
Marzieh Mirzae,
Mohammad Hossein Abbasi,
Gholam Ali Shahidi,
Qodsiye Hosseinifakhr,
Farzad Sina,
Seyed Amirhassan Habibi
Publication year - 2021
Publication title -
journal of advances in medical and biomedical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.113
H-Index - 12
ISSN - 2676-6264
DOI - 10.30699/jambs.29.136.257
Subject(s) - dyskinesia , parkinson's disease , incidence (geometry) , levodopa , medicine , disease , diabetes mellitus , pediatrics , physical medicine and rehabilitation , endocrinology , physics , optics
Parkinson’s disease (PD) is a systemic neurodegenerative disorder, affecting dopaminergic interactions inside the basal ganglia; finally, it results in an intermittent transfer of unwanted stimulatory signals into the corticospinal tract and disease manifestations. The corticospinal tract is the final affected portion of dopaminergic neurons through inhibition or stimulation of thalamic stimulatory signals to the motor cortex as a result of basal ganglia neuronal interactions (1-3).
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