Chronic Caffeine Ingestion Down-Regulates Liver and Visceral Adipose Tissue Inflammatory Gene Expression in High-Fat Diet-Induced Obesity | Zendy

Seyed Dara Hosseini | Zendy; Rahman Rahimi | Zendy; Mehdi Abbaspoor | Zendy

Open Access

Chronic Caffeine Ingestion Down-Regulates Liver and Visceral Adipose Tissue Inflammatory Gene Expression in High-Fat Diet-Induced Obesity

Author(s) -

Seyed Dara Hosseini,

Rahman Rahimi,

Mehdi Abbaspoor

Publication year - 2021

Publication title -

journal of advances in medical and biomedical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.113

H-Index - 12

ISSN - 2676-6264

DOI - 10.30699/jambs.29.135.189

Subject(s) - adipose tissue , ingestion , endocrinology , medicine , caffeine , obesity , gene expression , gene , inflammation , liver tissue , biology , biochemistry

10.30699/jambs.29.135.189 Background & Objective: Beverages containing caffeine have an anti-obesity function. Reduction of visceral adipose tissue (VAT) inflammation is considered an important strategy to ameliorate obesity compilations such as insulin resistance. This study aimed to investigate the effect of 8-week caffeine supplementation on the messenger RNA (mRNA) expression of fetuin-A (FetA) in the liver and nuclear factor kappa B (Nf-κb) and toll-like receptor 4 (Tlr4) in the VAT of rats with a highfat diet (HFD).

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