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The Analgesic and Anxiolytic Activity of Resveratrol Mediated by Different Sub-Types of α-Adrenoceptors of Anterior Cingulate Cortex Following Neuropathic Pain in Male Rats
Author(s) -
Mohammad Hassan Mirasheh,
Mohammad Reza Zohrehvand,
Reza Kazemi,
Zahra Bahari,
Farideh Bahrami,
Zohreh Jangravi,
Mehdi Graily
Publication year - 2020
Publication title -
journal of advances in medical and biomedical research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.113
H-Index - 12
ISSN - 2676-6264
DOI - 10.30699/jambs.28.129.183
Subject(s) - anxiolytic , analgesic , anterior cingulate cortex , neuropathic pain , cingulate cortex , cortex (anatomy) , neuroscience , anesthesia , medicine , psychology , central nervous system , receptor , cognition
10.30699/jambs.28.129.183 Background & Objective: The mechanism of analgesic and anxiolytic activity of resveratrol in neuropathic pain conditions remains obscure. The present study was conducted to examine whether the analgesic and anxiolytic activities of resveratrol are associated with α1and α2-adrenoceptors of the anterior cingulate cortex (ACC), which is a key area of the cortex in the pain process, following neuropathic pain in rats.

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