Effect of Different Doses of Vitamin A on β-HCG Production in Patients Suffering from Gestational Trophoblastic Disease | Zendy

Shokoufeh Hosseini | Zendy; Masoumeh Yousefi | Zendy; Maryam Ebrahimi | Zendy

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Effect of Different Doses of Vitamin A on β-HCG Production in Patients Suffering from Gestational Trophoblastic Disease

Author(s) -

Shokoufeh Hosseini,

Masoumeh Yousefi,

Maryam Ebrahimi

Publication year - 2020

Publication title -

journal of advances in medical and biomedical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.113

H-Index - 12

ISSN - 2676-6264

DOI - 10.30699/jambs.28.128.151

Subject(s) - gestational trophoblastic disease , medicine , vitamin , obstetrics , disease , gestation , gynecology , trophoblastic neoplasm , pregnancy , endocrinology , biology , genetics

10.30699/jambs.28.128.151 Background & Objective: Gestational trophoblastic disease (GTD) is a type of disease which is characterized by increased production of B-HCG by placental cells. Increased β-HCG production is due to increased proliferation of beta cells and lack of apoptosis. If left untreated, it can lead to malignancy. Almost 30-50 of GTD progresses to gestational trophoblastic neoplasia (GTN) in women over 40 years old. This study aimed to evaluate the effect of vitamin A doses (100,000 IU and 200,000 IU) on the decrement of β-HCG levels.

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