Cerasus microcarpa and Amygdalus scoparia Methanolic Extract Protect Cultured Cerebellar Granule Neurons Against β-amyloid-induced Toxicity and Oxidative Stress | Zendy

Nasim Ataei | Zendy; Maliheh Soodi | Zendy; Homa Hajimehdipoor | Zendy; Sholeh Akbari | Zendy; Mahshid Alimohammadi | Zendy

Open Access

Cerasus microcarpa and Amygdalus scoparia Methanolic Extract Protect Cultured Cerebellar Granule Neurons Against β-amyloid-induced Toxicity and Oxidative Stress

Author(s) -

Nasim Ataei,

Maliheh Soodi,

Homa Hajimehdipoor,

Sholeh Akbari,

Mahshid Alimohammadi

Publication year - 2020

Publication title -

journal of advances in medical and biomedical research

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.113

H-Index - 12

ISSN - 2676-6264

DOI - 10.30699/jambs.28.126.23

Subject(s) - oxidative stress , granule (geology) , toxicity , chemistry , scoparia , amyloid β , biology , biochemistry , botany , medicine , paleontology , disease , organic chemistry

10.30699/jambs.28.126.23 Background & Objective: Beta-amyloid peptide (Aβ) causes neural cell death and has a pivotal role in the progression of Alzheimer’s disease (AD). The prevention of Aβ-induced toxicity is a target for agents intend to treat Alzheimer’s disease. Our previous in vitro study indicated anti-cholinesterase and anti-oxidant activity of Amygdalus scoparia and Cerasus microcarpa methanolic extracts. In the present study, their neuroprotective effects against Aβ-induced toxicity are investigated .

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