Investigation of MexAB-OprM efflux pump gene expression in clinical isolates of pseudomonas aeruginosa isolated from Intensive Care Unit | Zendy

Masomeh Beig | Zendy; Mohammad Reza Arabestani | Zendy

Open Access

Investigation of MexAB-OprM efflux pump gene expression in clinical isolates of pseudomonas aeruginosa isolated from Intensive Care Unit

Author(s) -

Masomeh Beig,

Mohammad Reza Arabestani

Publication year - 2019

Publication title -

iranian journal of medical microbiology

Language(s) - English

Resource type - Journals

eISSN - 2345-4342

pISSN - 1735-8612

DOI - 10.30699/ijmm.13.2.142

Subject(s) - pseudomonas aeruginosa , efflux , microbiology and biotechnology , intensive care unit , medicine , bacteria , biology , intensive care medicine , biochemistry , genetics

DOI: Background and Aims: Pseudomonas aeruginosa is one of the most important pathogens of nosocomial infections, especially in the ICU (Intensive Care Unit), which has resistance to a wide range of antibiotics, especially Carbapenems. Among the most important resistance mechanisms of this bacteria against carbapenems are MexABOprM efflux pump. Therefore, the aim of this study was to evaluate the gene expression of MexAB-OprM efflux pump in clinical isolates of P. aeruginosa that isolated from ICU.

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