Investigation of Association Between adeA, adeB ,adeI Genes and Phenotypic Activity of Efflux Pump in Multiple Drug Resistant Acinetobacter baumannii Isolates | Zendy

Negin Sedighian Kashi | Zendy; Sahar Honarmand | Zendy; Fahimeh BaghbaniArani | Zendy

Open Access

Investigation of Association Between adeA, adeB ,adeI Genes and Phenotypic Activity of Efflux Pump in Multiple Drug Resistant Acinetobacter baumannii Isolates

Author(s) -

Negin Sedighian Kashi,

Sahar Honarmand,

Fahimeh BaghbaniArani

Publication year - 2019

Publication title -

iranian journal of medical microbiology

Language(s) - English

Resource type - Journals

eISSN - 2345-4342

pISSN - 1735-8612

DOI - 10.30699/ijmm.12.5.301

Subject(s) - acinetobacter baumannii , efflux , neisseriaceae , microbiology and biotechnology , acinetobacter , phenotype , gene , drug resistance , biology , medicine , antibiotics , pseudomonas aeruginosa , bacteria , genetics

IJMM 2018; 12(5): 301-310 Background and Aims: Acinetobacter baumannii is a major cause of nosocomial infections and is resistant to many antibiotics. Over expression of AdeABC and AdeIJK efflux pumps in Acinetobacter causes resistance to aminoglycosides and decreases the sensitivity of fluoroquinolones. The aim of this study was to investigate the phenotypic activity of the Acinetobacter baumanni isolates associated with presence of adeA, adeB, and adeI genes.

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