The Study of the Stable Expression of IpaB, the Virulence Factor in Shigella Sonnei, in Terms of Simultaneous Expression of Chaperone IpgC | Zendy

Fateme Nasrollahi Boroujeni | Zendy; Ali Asghar Deldar | Zendy

Open Access

The Study of the Stable Expression of IpaB, the Virulence Factor in Shigella Sonnei, in Terms of Simultaneous Expression of Chaperone IpgC

Author(s) -

Fateme Nasrollahi Boroujeni,

Ali Asghar Deldar

Publication year - 2018

Publication title -

iranian journal of medical microbiology

Language(s) - English

Resource type - Journals

eISSN - 2345-4342

pISSN - 1735-8612

DOI - 10.30699/ijmm.12.4.260

Subject(s) - shigella sonnei , virulence , shigella , virulence factor , microbiology and biotechnology , shigellosis , chaperone (clinical) , biology , bacteria , salmonella , medicine , genetics , gene , pathology

IJMM 2018; 12(4): 260-268 Background and Aims: The virulence plasmid of the Gram negative pathogen Shigella generates many virulence factors within the Ipa-mxi-spa region. Shigella spreads via fecal-oral and person-to-person transmission which causes human bloody diarrhea. In Asia alone, it is estimated that there are 125 million infections and 14,000 deaths due to shigellosis annually. IpaB is essential for Shigella infection and pathogenicity.

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