A Case Report of a Pregnant Woman with Chronic Hepatit B: Use of Tenofovir in Pregnancy | Zendy

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A Case Report of a Pregnant Woman with Chronic Hepatit B: Use of Tenofovir in Pregnancy

Author(s) -

Hülya Güven,

Aylin Arıcı,

Gözde Aktürk,

Özge Güner

Publication year - 2020

Publication title -

journal of basic and clinical health sciences

Language(s) - English

Resource type - Journals

eISSN - 2564-7288

pISSN - 2458-8938

DOI - 10.30621/jbachs.2020.807

Subject(s) - tenofovir , pregnancy , medicine , obstetrics , transmission (telecommunications) , chronic hepatitis , viral load , virology , gynecology , virus , human immunodeficiency virus (hiv) , biology , computer science , telecommunications , genetics

Objective: To overview the effects of tenofovir use in chronic Hepatit B in pregnancy and asses the effects on the vertical transmission of HBV from mother to baby. Case Report: We presented a pregnant woman who has Chronic Hepatit B with high viral load in the 26 week of her pregnancy. She took tenofovir in the 37 week of her pregnancy once a day along six days. Then she gave birth to a healthy baby at the 37 week of the pregnancy. Hepatit B Immunoglobulin (HBIG) and Hepatit B vaccine had applied to the baby. In the follow-up, the mother’s viral load was decreased. HBV DNA was not detected in the baby. Conclusion: Only six-day tenofovir use in this pregnant woman with chronic Hepatit B may contribute to preventing vertical transmission of HBV from mother to baby. However, the importance of HBIG and vaccination should not be forgotten.

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