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The present study was designed for detection the effect of formaldehyde in some biochemical and physiological parameters which included cholesterol , triglycerides and level of lipid profile and histopathological changes of some organs of the laboratory male rats Rattus norvegicus , thirty two of rats were divided into four groups , the first group administrated normal saline as control group while the three others groups administrated formaldehyde orally (10mg/kg body weight/day) for one , two and three months respectively . The results showed a significant increasing (P≤0.05) in level of cholesterol , LDL and VLDL in second, third and fourth groups compared with control group, while non-significant increasing in triglycerides and atherogenic index level for treated groups (second, third and fourth groups) compared with control group . Significant decreasing (P≤0.05) was observed in level of HDL for all treated groups by formaldehyde compared with control group . Also, the results showed histopathological changes as congestion , destroyed and thickness the walls of alveoli , hemorrhage and infiltration of inflammatory cells in lung . In addition to many damages in liver which included congestion of central vein , necrosis , enlargement of sinusoids , inflammation , hemorrhage and vacuolation of hepatocytes with hypertrophy the nuclei of its

Assessment of Lipoprotein and Histopathological Changes of Male Rats Rattus norvegicus Treated With Formaldehyde