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Molecular Detection and Evaluation of MLـ Resistance M. Pneumoniae Associated with Mutation in 23S RNA Gene among Iranian Patients with Respiratory Infections
Author(s) -
Iman Pouladi,
Reza Mirnejad,
Susan Rostampur,
Soghra Viesy,
Mohammad Niakan
Publication year - 2020
Publication title -
reports of biochemistry and molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.467
H-Index - 8
ISSN - 2322-3480
DOI - 10.29252/rbmb.9.2.223
Subject(s) - 23s ribosomal rna , gene , mutation , respiratory system , gene mutation , rna , medicine , biology , microbiology and biotechnology , genetics , ribosome
Mycoplasma pneumoniae is a common cause of community-acquired pneumonia. The global increased resistance of M. pneumoniae strains to macrolide (ML) has become a worrisome health problem. The widespread use of these medications has led to increased rate of reported ML-resistant M. pneumoniae (MRMP) throughout the world. This study was aimed to evaluate the resistance of M. pneumoniae against erythromycin due to mutations in the 23S rRNA gene of patients with respiratory infections in Iran.

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