Relative Expression of SOX2 and OCT4 in Oral Squamous Cell Carcinoma and Oral Epithelial Dysplasia | Zendy

Narges Ghazi | Zendy; Narges Aali | Zendy; Vahid-Reza Shahrokhi | Zendy; Farnaz Mohajertehran | Zendy; Nasrollah Saghravanian | Zendy

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Relative Expression of SOX2 and OCT4 in Oral Squamous Cell Carcinoma and Oral Epithelial Dysplasia

Author(s) -

Narges Ghazi,

Narges Aali,

Vahid-Reza Shahrokhi,

Farnaz Mohajertehran,

Nasrollah Saghravanian

Publication year - 2020

Publication title -

reports of biochemistry and molecular biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.467

H-Index - 8

ISSN - 2322-3480

DOI - 10.29252/rbmb.9.2.171

Subject(s) - sox2 , epithelial dysplasia , dysplasia , medicine , pathological , pathology , basal cell , carcinogenesis , cancer , stage (stratigraphy) , oncology , biology , gene , transcription factor , paleontology , biochemistry

Over 90% of oral cancers including oral squamous cell carcinoma (OSCC), originate from the oral cavity epithelium. Early detection for this lesion is as important. Evaluating cancer stem cell markers can improve the accuracy of early diagnosis, and be used as an OSCC prognostic indicator. We aimed to evaluate SOX2 and OCT4 gene expression among different grades of OSCC and oral epithelial dysplasia (OED) lesions.

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