The Prevalence of 23S rRNA Mutations in ML-Resistant M. pneumoniae Isolates to Clarithromycin in Patients with Respiratory Infections
Author(s) -
Hanieh Beikmohammadi,
Iman Pouladi,
Mohammad Reza Zolfaghari,
Mohammad Niakan
Publication year - 2020
Publication title -
reports of biochemistry and molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.467
H-Index - 8
ISSN - 2322-3480
DOI - 10.29252/rbmb.9.2.156
Subject(s) - 23s ribosomal rna , clarithromycin , mycoplasma pneumoniae , microbiology and biotechnology , broth microdilution , biology , macrolide antibiotics , ribosomal rna , minimum inhibitory concentration , antibiotics , gene , erythromycin , pneumonia , medicine , genetics , ribosome , rna
Mycoplasma pneumoniae is one of the widespread causes of community-acquired pneumonia (CAP). Over recent years, the widespread use of macrolides has led to the emergence of macrolide-resistant M.pneumoniae (MRMP) resulted from mutations at specific positions of domain V of the 23S rRNA gene.
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