Protective Effect of N-acetyl-cysteine Against Rat Liver Mitochondrial Toxicity Induced by CuSO4 | Zendy

Mohsen Rezaei | Zendy; Sohrab Rahmani | Zendy

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Protective Effect of N-acetyl-cysteine Against Rat Liver Mitochondrial Toxicity Induced by CuSO4

Author(s) -

Mohsen Rezaei,

Sohrab Rahmani

Publication year - 2020

Publication title -

qom univ med sci j

Language(s) - English

Resource type - Journals

eISSN - 2008-1375

pISSN - 1735-7799

DOI - 10.29252/qums.14.6.9

Subject(s) - toxicity , liver toxicity , cysteine , mitochondrial toxicity , chemistry , pharmacology , mitochondrion , biochemistry , biology , enzyme , organic chemistry

Received: 18 Jun, 2020 Accepted: 25 Aug, 2020 Abstract Background and Objectives: Copper sulfate (CuSO4) is a toxic substance with a broad range of applications; however, the ingestion of high levels of it cause a wide range of complications in the liver tissue. According to previous studies, mitochondria are potential targets for CuSO4 toxicity. The present study aimed to examine the role of Nacetyl-cysteine as an antioxidant agent in the protection of mitochondria against toxicity induced by CuSO4.

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