Comparison of the Protective Effects of Curcumin and Nanocurcumin on Acrolein Induced Mitochondrial Toxicity Isolated from Rat Liver | Zendy

Behnaz Shafie | Zendy; Jalal Pourahmad | Zendy; Mohsen Rezaei | Zendy

Open Access

Comparison of the Protective Effects of Curcumin and Nanocurcumin on Acrolein Induced Mitochondrial Toxicity Isolated from Rat Liver

Author(s) -

Behnaz Shafie,

Jalal Pourahmad,

Mohsen Rezaei

Publication year - 2019

Publication title -

qom univ med sci j

Language(s) - English

Resource type - Journals

eISSN - 2008-1375

pISSN - 1735-7799

DOI - 10.29252/qums.13.9.1

Subject(s) - acrolein , curcumin , toxicity , liver toxicity , mitochondrial toxicity , chemistry , pharmacology , biochemistry , toxicology , medicine , biology , organic chemistry , catalysis

Received: 6 Jul, 2019 Accepted: 20 Oct, 2019 Abstract Background and Objectives: Contact with acrolein rapidly reduces intracellular glutathione and its antioxidant capacity and causes mitochondrial dysfunction. The use of some polymeric nanocurcumin increases the stability of curcumin. In this study, the effect of these two, was investigated on acrolein-induced toxicity in mitochondria isolated from rat liver cells.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research