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The Interactive Effect of Crocin Supplementation on the Alteration of Malondialdehyde and Cardiomyocyte Catalase in Male Rats Poisoned with Hydrogen Peroxide
Author(s) -
Afsaneh Seyfi,
Fereshteh Shahidi,
Mojtaba Salehpor
Publication year - 2019
Publication title -
qom univ med sci j
Language(s) - English
Resource type - Journals
eISSN - 2008-1375
pISSN - 1735-7799
DOI - 10.29252/qums.13.8.5
Subject(s) - malondialdehyde , catalase , hydrogen peroxide , crocin , chemistry , peroxide , biochemistry , pharmacology , medicine , oxidative stress , organic chemistry
Background and Objectives: Active oxygen species (ROS) are direct or indirect causes of cell damage. Continuously active heart muscle as an oxidative tissue is one of the tissues susceptible to oxidative damage. Malondialdehyde is one of the lipid peroxidation products, which is considered in the studies as an indicator of oxidative damage level. Crocin is also a carotenoid extracted from Saffron, which can affect the damage level with its antioxidant properties. In this study, the effect of crocin supplementation on the alteration of Malondialdehyde and catalase cardiomyocyte, was investigated in male rats poisoned with hydrogen peroxide.

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