Effect of Ghrelin on Viability, Proliferation, and Apoptosis in Human Granulosa Cells, In Vitro | Zendy

Faeze Astine Goorabi | Zendy; Farzaneh Nazari-Serenjeh | Zendy; Mohammad Hadi Bahadori | Zendy

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Effect of Ghrelin on Viability, Proliferation, and Apoptosis in Human Granulosa Cells, In Vitro

Author(s) -

Faeze Astine Goorabi,

Farzaneh Nazari-Serenjeh,

Mohammad Hadi Bahadori

Publication year - 2019

Publication title -

qom univ med sci j

Language(s) - English

Resource type - Journals

eISSN - 2008-1375

pISSN - 1735-7799

DOI - 10.29252/qums.13.2.11

Subject(s) - ghrelin , apoptosis , in vitro , microbiology and biotechnology , viability assay , chemistry , endocrinology , biology , hormone , biochemistry

Received: 22 Sep, 2018 Accepted: 26 Jan, 2019 Abstract Background and Objectives: Ghrelin is a peptide hormone that was initially derived from stomach and introduced as an endogenous ligand for the growth hormone secretagogue receptor. Ghrelin is fundamentally involved in regulation of nutrition and energy homeostasis in the body. It has been shown that ghrelin has an important role in fertility in women. The purpose of the present study was to assess the effect of ghrelin on viability, growth, and apoptosis of human granulosa cells culture in vitro.

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