The Effect of Hydroalcoholic Extract of Tamarix dioica Flower on Thioacetamide - Induced Histomorphological Changes in Rats | Zendy

Mohammad Ebrahim َAkbari | Zendy; Abbas Jamshidian | Zendy; Mehdi Rasekh | Zendy; Sedighe Esmaeelzadeh Behabadi | Zendy; Mohammad Reza Hajinezhad | Zendy

Open Access

The Effect of Hydroalcoholic Extract of Tamarix dioica Flower on Thioacetamide - Induced Histomorphological Changes in Rats

Author(s) -

Mohammad Ebrahim َAkbari,

Abbas Jamshidian,

Mehdi Rasekh,

Sedighe Esmaeelzadeh Behabadi,

Mohammad Reza Hajinezhad

Publication year - 2020

Publication title -

qom univ med sci j

Language(s) - English

Resource type - Journals

eISSN - 2008-1375

pISSN - 1735-7799

DOI - 10.29252/qums.13.12.65

Subject(s) - thioacetamide , tamarix , urtica dioica , botany , biology , traditional medicine , chemistry , medicine , biochemistry

Methods: Thirty adult male Wistar rats, were randomly divided into three groups of control (normal saline); negative control (thioacetamide 50 mg/kg) and group that received thioacetamide and T. dioica flower extract (200 mg/kg). The third group received the T. dioica flowers extract two weeks before the injection of thioacetamide and two weeks after the injection of thioacetamide. The healthy control group and the negative control group received normal saline. At the end of the experiment, blood samples, were obtained from the heart to determine lever enzymes aspartate aminotransferase (AST), alanine amino transaminase (ALT), blood urea nitrogen (BUN), and creatinine. After euthanasia, tissue samples, were examined using a light microscope after staining with haematoxylin-eosin. Data were analyzed by oneway ANOVA statistical test. Statistical significance was considered as p < 0.05.

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