Immunogenicity of N-CfTX-2 Antigen of Chironex fleckeri Jellyfish in Mice | Zendy

Hossein Honari | Zendy; Seyed Mojtaba Aghaie | Zendy; Hamed Jalilpour | Zendy

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Immunogenicity of N-CfTX-2 Antigen of Chironex fleckeri Jellyfish in Mice

Author(s) -

Hossein Honari,

Seyed Mojtaba Aghaie,

Hamed Jalilpour

Publication year - 2018

Publication title -

qom univ med sci j

Language(s) - English

Resource type - Journals

eISSN - 2008-1375

pISSN - 1735-7799

DOI - 10.29252/qums.12.9.47

Subject(s) - jellyfish , immunogenicity , antigen , biology , immunology , virology , fishery

21 Apr, 2018 Received: 13 Jun, 2018 Accepted: Abstract Background and Objectives: Chironex. fleckeri is the most toxic and dangerous marine species. CfTX-2 is one of the antigenic proteins of jellyfish venom that has been suggested for stimulation of the immune system, for treatment, and as a candidate for vaccine. The purpose of this study was designing, optimization, synthesis, and expression of the N-CfTX-2 gene in E. coli and investigation of the production of antibodies and immunization in mice.

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