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Methods: In this laboratory experimental study, at first, extract of the plant was prepared using maceration method. The effect of different concentrations of the extract (0.001, 0.001, 0.1, 1, and 10mg/ml) was investigated on the viability of MCF-7 cells using MTT assay method. Also, the effects of doses of 1, 0.1, and 0.01mg/ml of the extract, was evaluated on BAX and KAI1 genes using real-time PCR. The data were analyzed using one way AN0VA test.

majallah-i dānishgāh-i ̒ulūm-i pizishkī-i qum./majallah-i dānishgāh-i ̒ulūm-i pizishkī-i qum.

The Cytotoxic Effects of Hydroalcoholic Extract of Aerial Parts of Scrophularia striata on MCF-7 Cell Line and Evaluation of BAX and KAI1 Genes Expression