The Effect of Intrahippocampal Injection of Ghrelin on Morphine-Induced Amnesia by Passive Avoidance Task in Male Laboratory Rats | Zendy

Niloufar Darbandi | Zendy; Farzaneh Nazari Serenjeh | Zendy; Parham Moradi | Zendy

Open Access

The Effect of Intrahippocampal Injection of Ghrelin on Morphine-Induced Amnesia by Passive Avoidance Task in Male Laboratory Rats

Author(s) -

Niloufar Darbandi,

Farzaneh Nazari Serenjeh,

Parham Moradi

Publication year - 2018

Publication title -

qom univ med sci j

Language(s) - English

Resource type - Journals

eISSN - 2008-1375

pISSN - 1735-7799

DOI - 10.29252/qums.12.8.19

Subject(s) - amnesia , morphine , ghrelin , retrograde amnesia , hippocampus , psychology , task (project management) , anesthesia , medicine , neuroscience , cognitive psychology , receptor , management , economics

Received: 14 Mar, 2018 Accepted: 13 May, 2018 Abstract Background and Objectives: Ghrelin is a peptide hormone, which is secreted by stomach cells and has an important role in the metabolism and energy homeostasis. This hormone crosses the blood-brain barrier and enters the hippocampus, where it affects the learning process and memory. In the present study, the effect of intrahippocampal injection of ghrelin on morphine-induced amnesia was investigated using passive avoidance learning model in experimental male rats.

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