Investigation of Clinical Manifestations of Congenital Metabolic Liver Diseases in Patients Referring to Children Medical Center during 2013-2015

Results: During the years 2013-2015, out of 87 children with congenital liver disease referred to the Children Medical Center Hospital, 48 children were female (55%) and 39 were male (45%). Pallor (90%), hepatomegaly (75%), abdominal pain (70%), vomiting (70%), and jaundice (70%), were the most commonly reported clinical signs in these patients, tyrosinemia was reported as the most common causes of metabolic liver disease (20 cases). Other causes included cystic fibrosis (15 cases), glycogen storage disease (12 cases), galactosemia (8 cases), and Wilson disease (7 cases).