Cytotoxicity Effect and Changes in the Expression of Caspase-9 Gene in Breast Cancer Cell Line (MCF-7) Treated with the Extract of Oscillatoria Cyanobacteria | Zendy

Ali Salehzadeh | Zendy; Fatemeh Sayyad Delshadpour | Zendy; Ataollah Sadat Shandiz | Zendy

Open Access

Cytotoxicity Effect and Changes in the Expression of Caspase-9 Gene in Breast Cancer Cell Line (MCF-7) Treated with the Extract of Oscillatoria Cyanobacteria

Author(s) -

Ali Salehzadeh,

Fatemeh Sayyad Delshadpour,

Ataollah Sadat Shandiz

Publication year - 2018

Publication title -

qom univ med sci j

Language(s) - English

Resource type - Journals

eISSN - 2008-1375

pISSN - 1735-7799

DOI - 10.29252/qums.12.1.26

Subject(s) - mcf 7 , cytotoxicity , oscillatoria , cyanobacteria , breast cancer , cell culture , gene expression , cancer cell lines , cancer research , caspase 3 , apoptosis , biology , gene , cancer , microbiology and biotechnology , cancer cell , human breast , programmed cell death , biochemistry , genetics , in vitro , bacteria

Accepted: 31 Jan, 2017 Abstract Background and Objectives: Breast cancer is one of the most common cancers in women around the world. Problems, such as treatment failure, drug resistance, heavy costs, other problems associated with the treatment of this type of cancer, have attracted the interest of many researchers to cyanobacteria, since these microorganisms have fewer side-effects compared to chemical drugs. In the present research, the effect of Oscillatoria extract was investigated on the viability of MCF7 cell line as well as caspase-9 gene expression.

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