Association the Study of between CGA rs6631A>T Gene Polymorphism with the Risk of Male Infertility

Background and Objective: The CGA gene encodes alpha subunit of glycoprotein hormones that are involved in the fertility process. The aim of this study was to evaluate the association between glycoprotein hormones, alpha polypeptide (CGA) rs6631A> T gene polymorphism with the risk of men infertility with azoospermia or severe oligozoospermia. Materials and Methods: This study was conducted in a case-control study on 200 blood samples consisting of 100 samples of severe oligozoospermia or azoospermia men and 100 blood samples of healthy men with normal fertility and lack of a family history of infertility. In this study, we used PCR-RFLP method to evaluate genotype frequencies of