Association of Hemoglobin Electrophoretic Phenotype with Human Parvovirus B19 infection among Pregnant Women attending Abuja Tertiary Hospital, Nigeria
Author(s) -
Idris Nasir Abdullahi,
Hafeez Aderinsayo Adekola,
Anthony Uchenna Emeribe,
Abdurrahman El-Fulaty Ahmad,
Thairu Yunusa,
Maryam Muhammad Zakari,
Nkechi Blessing Onukegbe,
Sanusi Musa,
Dele Ohinoyi Amadu,
Bamidele Soji Oderinde
Publication year - 2020
Publication title -
medical laboratory journal
Language(s) - English
Resource type - Journals
ISSN - 2538-4449
DOI - 10.29252/mlj.14.3.33
Subject(s) - medicine , phenotype , hemoglobin , parvovirus , obstetrics , immunology , pediatrics , biology , virus , genetics , gene
Background and Objectives: Human parvovirus B19 (B19V) has singular tropism to erythropoietic cells and causes a wide range of complications in some fetuses of infected pregnant women, especially those with hemoglobinopathies. This study aimed to determine association of hemoglobin electrophoretic patterns and other risk factors of B19V in pregnant women attending University of Abuja Teaching Hospital (UATH), Abuja, Nigeria. Methods: Blood samples were collected from 200 pregnant women and screened for antiB19V Immunoglobulin-M (IgM), Immunoglobulin-G (IgG) and hemoglobin phenotypic pattern using enzyme immunosorbent assay and Minicap Flex Piercing Electrophoresis, respectively. Structured questionnaires were used to collate sociodemographic variables and associated
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