The Effect of Gallic Acid Supplement and Resistance Exercise on the Bio-markers of Liver in Intoxicated Male Rats of Anabolic Steroid

Background and Objectives: Liver is one of the vital organs of the human body. Antioxidants have been shown to play important roles in reducing liver injuries. The aim of this study was to examine the effects of gallic acid supplementation and resistance exercise on liver damage biomarkers in male rats intoxicated by steroid anabolic. Materials and Methods: Forty-two male Wistar rats were randomly divided into six equal groups: control, sham, steroid anabolic (5 mg/kg), steroid anabolic (5 mg/kg) + gallic acid supplementation (50 mg/kg), steroid anabolic (5 mg/kg) + resistance exercise, and steroid anabolic (5 mg/kg) + gallic acid supplementation (50 mg/kg) + resistance exercise. Except for control and sham groups, all groups received (injection) steroid anabolic at a dose of 5 mg / kg body weight once a week. The resistance exercise protocol was comprised of three weekly exercise sessions by 5 rep/3 set of climbing ladder for eight weeks. Data were analyzed via ANOVA and Tukey's post hoc test at a significance level of