Genotyping of Individuals with Hemoglobinopathies in Beja Tribes and Other Minor Groups in Port Sudan, Eastern Sudan | Zendy

Mohammed Omer Abaker Gibreel | Zendy; Mubarak El Saeed Elkarsani | Zendy; Munsour Mohammed Munsour | Zendy; Hanan Babeker El Taher | Zendy

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Genotyping of Individuals with Hemoglobinopathies in Beja Tribes and Other Minor Groups in Port Sudan, Eastern Sudan

Author(s) -

Mohammed Omer Abaker Gibreel,

Mubarak El Saeed Elkarsani,

Munsour Mohammed Munsour,

Hanan Babeker El Taher

Publication year - 2018

Publication title -

medical laboratory journal

Language(s) - English

Resource type - Journals

ISSN - 2538-4449

DOI - 10.29252/mlj.12.6.40

Subject(s) - genotyping , port (circuit theory) , minor (academic) , medicine , geography , ancient history , genetics , genotype , biology , history , political science , gene , law , electrical engineering , engineering

Background and objectives: This study aimed to characterize the spectrum of β-thalassemia mutations and haplotypes of sickle cell anemia in Beja tribes and other minor groups living in Port Sudan, Sudan. Methods: This descriptive cross-sectional study was carried out from March 2011 to July 2013. Overall, 209 anemic patients were screened for hemoglobinopathy by capillary electrophoresis. The subjects were genotyped for β-thalassemia mutation by amplified refractory mutation system and for sickle cell haplotype by restriction-fragment length

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