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Background and Objectives: Obesity is a global health problem that could lead to cardiovascular disease, diabetes and cancer. Polygenic obesity is caused by multiple factors, such as lack of exercise and excess food intake. In this study, we evaluated effects of 12 weeks of high-intensity interval training (HIIT) and isocratic moderate-intensity training (MIT) on anthropometric indices and insulin resistance in rats fed with a high-fat diet (HFD). Methods: Twenty-five male Wistar rats (mean age of 5-6 weeks) were divided into three groups: control group (HFD, N=5), HFD+ MIT (N=10) and HFD+ HIIT (N = 10). After placing the subjects on a HFD for 13 weeks, the exercise groups performed trainings for 12

medical laboratory journal

Effects of Endurance Training and Isocaloric High Intensity Interval Training on Anthropometric Indices and Insulin Resistance in High Fat Diet-Fed Wistar Rats