The Role of Angiogenesis in Colorectal Polyps and Cancer, a Review
Author(s) -
Hamid Asadzadeh Aghdaei,
Zahra Pezeshkian,
Meghdad AbdollahpourAlitappeh,
Ehsan Nazemalhosseini Mojarad,
Mohammad Reza Zali
Publication year - 2018
Publication title -
medical laboratory journal
Language(s) - English
Resource type - Journals
ISSN - 2538-4449
DOI - 10.29252/mlj.12.4.1
Subject(s) - medicine , colorectal cancer , angiogenesis , cancer , general surgery , oncology , gastroenterology
Colorectal cancer remains a leading cause of morbidity and mortality worldwide. Most colorectal cancers begin as a growth of tissue called a polyp, some types of which can change into cancer over the course of several years. Angiogenesis, the formation of new blood vessels, is known to play a key role in the initiation, growth and progression of polyp and colorectal cancer. In this review, we discuss the mechanisms involved in colorectal cancer and polyp angiogenesis.
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