Evaluation of Antibiotic Resistance Patterns and Frequency of Carbapenemase-Producing Acinetobacter baumannii Isolates by the Carbacineto NP Test | Zendy

shahraki zahedani Shahram | Zendy; Rogaye Javadi | Zendy

Open Access

Evaluation of Antibiotic Resistance Patterns and Frequency of Carbapenemase-Producing Acinetobacter baumannii Isolates by the Carbacineto NP Test

Author(s) -

shahraki zahedani Shahram,

Rogaye Javadi

Publication year - 2018

Publication title -

medical laboratory journal

Language(s) - English

Resource type - Journals

ISSN - 2538-4449

DOI - 10.29252/mlj.12.2.13

Subject(s) - acinetobacter baumannii , microbiology and biotechnology , acinetobacter , antibiotics , antibiotic resistance , biology , medicine , bacteria , pseudomonas aeruginosa , genetics

Background and Objectives: Acinetobacter baumannii is an opportunistic pathogen associated with nosocomial infections. Treatment of infections caused by this bacterium has become challenging due to increasing rate of resistance to a wide range of antibiotics such as carbapenems. One of the main mechanisms of resistance to carbapenems is the production of carbapenemase. The objective of this study was to evaluate antibiotic resistance patterns and frequency of carbapenemase-producing A. baumannii strains using the CarbAcineto NP Test. Methods: In this descriptive cross-sectional study, 130 A. baumannii isolates were collected from clinical specimens of teaching hospitals in Zahedan in 2016. After determining the antibiotic resistance patterns, all A. baumannii isolates were examined using the phenotypic method of CarbAcineto NP test to evaluate production of carbapenemase

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