Anti-Leishmanial Activity of Pelargonium roseum Essential Oil on Growth of Leishmania infantum Promastigotes | Zendy

Mohaddeseh Abouhosseini Tabari | Zendy; Mohammad Reza Youssefi | Zendy; Bibi Razieh Hosseini Farash | Zendy; Mohammad Amin Ebrahimi | Zendy; Niki Nabavi Mousavi | Zendy; Elham Moghaddas | Zendy

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Anti-Leishmanial Activity of Pelargonium roseum Essential Oil on Growth of Leishmania infantum Promastigotes

Author(s) -

Mohaddeseh Abouhosseini Tabari,

Mohammad Reza Youssefi,

Bibi Razieh Hosseini Farash,

Mohammad Amin Ebrahimi,

Niki Nabavi Mousavi,

Elham Moghaddas

Publication year - 2017

Publication title -

medical laboratory journal

Language(s) - English

Resource type - Journals

ISSN - 2538-4449

DOI - 10.29252/mlj.11.5.36

Subject(s) - leishmania infantum , leishmania , leishmaniasis , biology , essential oil , geraniol , microbiology and biotechnology , botany , immunology , visceral leishmaniasis , parasite hosting , world wide web , computer science

Background and Objectives: Due to adverse effects of pentavalent antimonial treatment of visceral leishmaniasis using herbal medicines has received a lot of attention. In this study, we evaluated inhibitory activity of Pelargonium roseum essential oil on growth of Leishmania infantum promastigotes, and compared it with that of Glucantime. Methods: Inhibitory effects of different concentrations (1, 2.5, 5, 10, 25, 50 and 100 μL/ml) of P. roseum essential oil on the growth of L. infantum promastigotes were studied by MTT assay after 24 and 48 hours. All the data were analyzed by one-way analysis of variance. The effect of the essential oil was later compared with that of standard dose of

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