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Myocardial infarction is one of the most common causes of death worldwide. Venous thrombolytic therapy is one of the important treatments in the acute phase of this disease. Although benefits of thrombolytic therapy is approved in patients aged less than 75 years, beneficial effects of this treatment in old patients is controversial. The aim of our study was evaluation of venous streptokinase side effect in old patients. Methods: This cross-sectional descriptive study was conducted on 100 patients with acute myocardial infarction that received venous streptokinase ; Then, blood, cardiovascular and allergic side effects were evaluated. The data were analyzed, using SPSS. Results: Our patients consisted of 82 men and 18 women with a mean age of 11.7 years (± 61.7) . These patients were divided into two groups of under and above 70 years old. Although cardiac complications were the most common side effect of streptokinase in both groups, we did not find any significantly different streptokinase’s side effects between the two groups except for sinus bradycardia (p=0.04) and hypotension (p=0.02). Conclusions: Although there were a few complications of streptokinase in old patients, this treatment in these patients especially in centers without emergency angioplasty facility should be considered.

Survey side effect of intravenous Streptokinase in old patients with acute myocardial infarction.