Study on the effects of consumption of milk containing Artemia urmiana and Lactobacillus acidophilus on serum lipid profiles in rats that fed whit high-fat food

Hyperlipidemia is one of the crucial factors in the occurrence of cardiovascular diseases. The present study aimed to examine the effect of Artemia urmiana on Lactobacillus acidophilus growth in probiotic milk and their effect on serum lipid profiles in rats fed with high fat diet. Materials and Methods: To determine effects of different doses (0%, 1%, 2%, 3%) of Artemia urmiana on growth of probiotic bacteria Lactobacillus acidophilus, 0.33 g of lyophilized Lactobacillus acidophilus was separately added to one liter of sterilized low fat milk. Sixty male Wistar rats were then divided into 6 groups of 10, and were fed with different doses of probiotic milk containing Artemia urmiana for 60 days. Blood samples were taken from all the groups at the end of day 60 to measure cholesterol, triglyceride, LDL-C and HDL-C. Results: The study results indicated that the increasing concentration of Artemia urmiana has a positive effect on the growth Lactobacillus acidophilus in milk probiotic. Also groups receiving 3 percent of Artemia urmiana powder had the lowest serum cholesterol and the highest serum triglyceride levels. Conclusion: Overall Artemia urmiana was found effective on the growth of probiotic Lactobacillus acidophilus in milk. Daily consumption of different doses of Artemia urmiana and lactobacillus acidophilus in milk can improve serum lipid profile through reduction of cholesterol, triglycerides, LDL-C and increasing HDL-C levels.