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Alzheimer’s disease leads to negative effects on the individual's physical, psychological and cognitive conditions. Multi-sensory stimulation helps the patients to promote their physical, psychological and cognitive condition. The aim of this research is to determine the effect of multisensory stimulation on cognitive status of patients with Alzheimer’s disease; they wereresidents of Fereshtegan center for people with Alzheimer disease during the year of 2012. Materials and Methods: This is a clinical trial performed on two groups of control and experiment. 52 subjects were selected through random sampling. The experiment group underwent 20 sessions of multi-sensory stimulation, each lasting 45 minutes. Data were collected through psychiatric records, a demographic questionnaire, and the brief questionnaire used for mental status examination. Results: Multi-sensory stimulation had a significant impact effect on the cognitive status of patients in the experiment group after several sessions of sensory stimulation test as compared to before the intervention and also in comparison with the control group. Cognitive status of the participants in the experimental group was improved. Also, the mean score of the brief mental status examination of the experiment group was significantly more than that of the control group, which shows that the intervention Conclusion: Multi-sensory stimulation can be an effective way to improve the cognitive state of patients with Alzheimer's disease. Further studies are recommended on different subjects with larger sample size to further confirm the results of this study.

The effect of multi-sensory stimulation (MSS) on cognitive status of women with Alzheimer’s disease in Fereshtegan elderly care center