Effect of biogenic selenium nanoparticles on ERG11 and CDR1 gene expression in both fluconazole-resistant and -susceptible Candida albicans isolates | Zendy

Nasrin Parsamehr | Zendy; Sasan Rezaie | Zendy; Sadegh Khodavaisy | Zendy; Samira Salari | Zendy; Sanaz Hadizadeh | Zendy; Mohammad Kord | Zendy; Seyyed Amin Ayatollahi Mousavi | Zendy

Open Access

Effect of biogenic selenium nanoparticles on ERG11 and CDR1 gene expression in both fluconazole-resistant and -susceptible Candida albicans isolates

Author(s) -

Nasrin Parsamehr,

Sasan Rezaie,

Sadegh Khodavaisy,

Samira Salari,

Sanaz Hadizadeh,

Mohammad Kord,

Seyyed Amin Ayatollahi Mousavi

Publication year - 2017

Publication title -

current medical mycology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.369

H-Index - 6

eISSN - 2423-3439

pISSN - 2423-3420

DOI - 10.29252/cmm.3.3.16

Subject(s) - candida albicans , selenium , azole , fluconazole , corpus albicans , microbiology and biotechnology , gene , gene expression , biology , chemistry , antifungal , biochemistry , organic chemistry

Candida albicans is the most common Candida species (sp.) isolated from fungal infections. Azole resistance in Candida species has been considerably increased in the last decades. Given the toxicity of the antimicrobial drugs, resistance to antifungal agents, and drug interactions, the identification of new antifungal agents seems essential. In this study, we assessed the antifungal effects of biogenic selenium nanoparticles on C. albicans and determined the expression of ERG11 and CDR1 genes.

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