The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat | Zendy

Razieh Dehghanian | Zendy; Seyyed Ebrahim Hosseini | Zendy; Esfandiar Sharifi | Zendy; Davood Moghadamnia | Zendy

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The Effects of Taraxacum Officinale Alcoholic Extract on Serum Thyroid Hormone Levels in Adult Male Rat

Author(s) -

Razieh Dehghanian,

Seyyed Ebrahim Hosseini,

Esfandiar Sharifi,

Davood Moghadamnia

Publication year - 2018

Publication title -

alborz university medical journal

Language(s) - English

Resource type - Journals

ISSN - 1735-6679

DOI - 10.29252/aums.7.3.213

Subject(s) - taraxacum officinale , hormone , thyroid , adult male , dandelion , thyroid hormones , medicine , traditional medicine , biology , endocrinology , pathology , alternative medicine , traditional chinese medicine

Background: Taraxacum Officinale is a medical plant with antioxidant benefit effects. The aim of the present study is to evaluate the effect of Taraxacum Officinale alcoholic extract on serum thyroid hormone levels in adult male rat. Material and Methods: In this experimental study,45 adult male wistar rats were approximate average weight body of 200-250 gr were divided in to 5 groups of 9. Control ,sham ,and three experimental groups which received 50,100,150mg/kg of Taraxacum Officinale alcoholic extract by used gavage method. After this period (14 days) blood sample were collected and after measuring the amount of thyroid hormones of T3,T4,TSH hormones, data were analyzed by using SPSS software , ANOVA and t-test. Results: The results showed that body weight average and serum level of T4 hormone in receiving maximum dose of Taraxacum Officinale alcoholic extract showed significant decrease comparing to control group. T3 serum level in experimental groups receiving Taraxacum Officinale alcoholic extract didn't show any significant difference comparing to control group. TSH serum level in experimental groups receiving Taraxacum Officinale alcoholic extract showed significant decrease comparing to control group (p<0.05). Conclusion: The Taraxacum Officinale alcoholic extract reduced serum thyroid hormone levels in adult male rat.

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